Objective: The aim in this study was to synthesize a novel chitosan derivative, galactosylated chitosan (GC), and prepare norcantharidin-associated galactosylated chitosan nanoparticles (NCTD-GC-NPs) with GC as hepatocyte-targeting carriers and norcantharidin (NCTD) as model drug against primary liver carcinoma.
目的:制备含有半乳糖基团的N-乳糖酰壳聚糖(galactosylated chitosan, GC)作为新型肝靶向药物载体。
METHODS Norcantharidin-associated galactosylated chitosan nanoparticles were achieved by ionic cross-linkage process with galactosylated chitosan as carrier.
方法以N-乳糖酰壳聚糖为载体,通过离子诱导法,制备去甲斑蝥素N-乳糖酰壳聚糖纳米粒。
N-alkyl-lactosylated-O,N-carboxymethyl chitosan are prepared by carboxymethyl-chitosan with alkyldehyde and lactose.
通过羧甲基壳聚糖与醛和乳糖反应制得N-烷基乳糖基-O,N-羧甲基壳聚糖,并以戊二醛为交联剂制成水凝胶;以人血清蛋白作为模型药物,初步探讨了该水凝胶对蛋白类药物的释放规律。
Isolation and enrichment of fetal nucleated red blood cells by using N-acetylgalactosamine-specific lectin;
N-乙酰半乳糖特异性植物凝素分离和富集胎儿有核红细胞
Objective To investigate the relationship between serum IgA1 molecular N- acetylgalactosamine abnormality and pathological manifestations of nephropathy among Mongolian ethnicity and Han group in Inner Mongolia region.
目的探讨内蒙地区蒙古族与汉族人群IgA肾病患者血清IgA1分子N-乙酰半乳糖胺异常程度与肾脏病理表现的关系。
Preparation and Characteristic of Norcantharidin-associated Galactosylated Chitosan Nanoparticles
去甲斑蝥素N-乳糖酰壳聚糖纳米粒的制备与性质研究
Preparation and in Vitro Antineoplastic Activity of Norcantharidi N-Associated Galactosylated Chitosan Nanoparticles
去甲斑蝥素N-乳糖酰壳聚糖纳米粒的制备与体外抗肿瘤活性
Preparation of norcantharidin N-galactosylated chitosan nanoparticles and its characteristics
去甲斑蝥素N-乳糖酰壳聚糖纳米粒的制备及其特性研究
Research on the aggregation behavior of N-maleoyl chitosan
N-马来酰化壳聚糖聚集行为的研究
Design,synthesis and characterization of N-palmityl-N′-aminoacyl chitosan derivatives
N-棕榈酰基-N′-氨基酰基壳聚糖衍生物的设计、合成及表征
Drug delivery study of temperature-responsive chitosan/poly(N-isopropylacrylamide) semi-interpenetrating-polymer-network beads
壳聚糖/聚N-异丙基丙烯酰胺温敏性珠状小球的药物释放研究
Stnthesis and Characterization of Thermoresponsive Hydrogels Cross-Linked with N-Malely Chitosan
N-马来酰化壳聚糖交联温敏性水凝胶的合成和性质研究
Study on the New Homogeneous Synthesis Method of N-Acyl Chitosan in Ionic Liquids
离子液体条件下N-酰化壳聚糖的均相合成新工艺研究
Preparation of N-caproyl Chitosan Nanoparticles Surface-modified with Glycyrrhizin and Its Stability in Vitro
甘草酸表面修饰N-己酰化壳聚糖纳米粒的制备及其稳定性研究
Synthesis of N-acyl chitosan derivatives and investigation of chitosan-modified docetaxel liposomes in vitro
N-酰化壳聚糖的合成及其修饰多西他赛脂质体的体外性质研究
Preparation of N-palmitoyl chitosan and improvement of pharmacokinetics of indirubin
N-软脂酰基壳聚糖的制备及其改善靛玉红水溶性的药动学研究
Modification of Poly (D, L-Lactic Acid) with Carboxymethyl Chitosan and Chitosan by Copolymerization or Blending;
聚乳酸与壳聚糖及羧甲基壳聚糖的改性研究
Preparation and performance of low-molecular weight N, O-carboxymethyl-chitosan
低聚N,O-羧甲基壳聚糖的制备与性能
Preparation and Characterization of N,O-Carboxymethyl Chitosan;
N,O-羧甲基壳聚糖的制备及表征
Use of Chitosan for Isolation of Beta-lactoglobulin from Whey Powder
壳聚糖法提取乳清粉中的β-乳球蛋白
Comparison of two chitosan deacetylation degree determination
壳聚糖脱乙酰度两种测定方法的比较
Co-immobilization of lactase and its application in production of low lactose milk
凹凸棒土—壳聚糖耦合固定化乳糖酶及其在低乳糖乳制备中的应用
COMPARISON OF ACTION PATTERN OF CHITINASE AND CHITOSANASE ON PARTIALLY N-ACETYLATED CHITOSAN
几丁质酶和壳聚糖酶对部分乙酰化壳聚糖作用方式的比较
