Tenecteplase based on the alteplase is the third generation thrombolytic agent,Th~(103)、Asn~(117) and Lys~(296)-His-Arg-Arg~(299) in alteplase molecule are replaced by Asn、Glu and Ala-Ala-Ala-Ala in tenecteplase.
替奈替普酶(Tenecteplase)是在阿替普酶(Alteplase)的基础上,用Asn、Glu和Ala-Ala-Ala-Ala代替其分子中的Th103、Asn117和Lys296-His-Arg-Arg2993个位点而得到的生物技术制品,属于新型的第3代溶栓药,具有体内半衰期长,溶栓效果好,溶栓时间短,纤维蛋白特异识别性强,使用方便及危险性低等特点。
Preparation of r-ETI affinity chromatograpy media and its application on purification of reteplase;
重组ETI亲和树脂的制备及其纯化瑞替普酶的研究
Clinical Evaluation on Thrombolytic Therapy with Reteplase for Injection on Acute Myocardial Infarction;
注射用瑞替普酶(r-PA)溶栓治疗急性心肌梗死的临床评价
Simulation,Construction and Expression of A Fusion Protein Made of 12 Peptides of Hirudin and Reteplase;
抗凝、溶栓双功能水蛭素12肽-瑞替普酶融合蛋白的模拟、构建与表达
Clinical observation on intravenous thrombolytic therapy with Alteplase in the treatment of 46 patients with acute myocardial infarction;
阿替普酶静脉溶栓治疗急性心肌梗死46例临床观察
Methods Two hundred and three patients were treated randomly by intravenous reteplase or alteplase.
方法共有203例AMI患者入选本研究,随机接受常规剂量(10 U+10 U)瑞替普酶或阿替普酶(艾通立)溶栓治疗,观察急性期病死率、心肌梗死并发症以及不良事件发生率。
Studies on Denaturation, Renaturation and Purification of Reteplase;
溶栓新药瑞替普酶（Reteplase）变复性及分离纯化的研究
Observation of Therapeutic Effect of Reteplace for Acute Myocardial Infarction
瑞替普酶溶栓治疗急性心肌梗死的疗效观察
The Clinical Contrast Research for Treating Acute Myocardial Infarction by Reteplase and Urokinase;
瑞替普酶与尿激酶治疗急性心肌梗死的临床对比研究
Clinical study of reteplase and urokinase in treatment of patients with acute myocardial infarction
瑞替普酶和尿激酶治疗急性心肌梗死的临床研究
Clinical study of reteplase and enoxaparin as reperfusion therapy in the patients with acute myocardial infarction
依诺肝素辅助瑞替普酶静脉溶栓治疗急性心肌梗死的临床研究
Clinical research on thrombolytic therapy of reteplase for acute myocardial infarction
应用瑞替普酶溶栓治疗急性心肌梗死的临床研究
Effect of reteplase thrombolytic therapy on cardiac function in patients with AMI
瑞替普酶对前壁及广泛前壁心肌梗死患者溶栓前后心脏功能观察
Posterior Vitreous Detachment Induced by Intravitreal Injection of Lysine-plasminogen and Reteplase in the Rabbit;
兔眼玻璃体腔联合注射赖氨酸—纤溶酶原和瑞替普酶诱导玻璃体后脱离的实验研究
Comparison of Curative Effect of Reteplase and Recombinant Streptokinase in the Patients with ST-Elevation Myocardial Infarction
急诊应用瑞替普酶、重组链激酶溶栓治疗ST段抬高型心肌梗死临床分析
Construction of a Retplase, Its Mutants and Expression in E. Coli and CHO Cells;
瑞替普酶（rPA）及其突变体的构建和在大肠杆菌与CHO细胞中的表达研究
GC determination of terprenone capsules
气相色谱法测定替普瑞酮胶囊的含量
Determination of Teprenone in rabbit plasma by RP-HPLC
RP-HPLC测定家兔血浆中的替普瑞酮
The Study on the Effect of Teprenone on Steroids-induced Gastric Mucosal Damage;
替普瑞酮对类固醇致胃黏膜损伤的保护作用
The Reteplase Project Management Research of FDZJ Stock Co.Ltd.;
FDZJ公司的瑞特普酶（Reteplase）项目管理的实证研究
Suppressive Effect of Teprenone on Chronic Atrophic Gastritis in Rats and Its Correlative Mechanism;
替普瑞酮对大鼠慢性萎缩性胃炎的干预作用及机制初探
Observation on Curative Effect of Treating HP-related Digestive Ulcer With Teprenone
替普瑞酮佐治幽门螺杆菌相关性胃溃疡疗效观察
A drug used in the treatment of hypertension that functions by inhibiting the enzymes that activate angiotensin.
卡普多普瑞尔一种用于治疗高血压的药物，该药通过抑制激活高血压素的酶起作用
Study of the Preconditioning Combination of Oral Administration of Geranylgeranylacetone and Local Somatothermal Stimulation for Conferring Tolerance Against Ischemia-reperfusion Injury in Rat Livers;
口服替普瑞酮联合局部躯体热刺激对抗大鼠肝脏缺血再灌注损伤的研究
