OBJECTIVE To prepare nonviral vector of solid lipid nanoparticles carrying protamine-pDNA complex(PD-SLN),to develop a Multifunctional Envelope-type Nano Device(MEND) structure,in which the core of a plasmid DNA,condensed by a polycation,is encapsulated by a lipid envelope,then the nanoparticles characteristics,the protection ability and the DNA release property in vitro were evaluated.
目的制备非病毒基因载体载鱼精蛋白-pDNA复合物的固体脂质纳米粒(PD-SLN),PD-SLN由多聚阳离子缩合DNA内核与一个脂质外壳组成,从而构成多功能信封式纳米载体(multifunctional envelope-type nano device,MEND)结构,研究其特征,对DNA的保护作用以及DNA的体外释放性质。
According to the national standards,a multi-functional loading-test machine was developed for testing the series of the performances of the car seat.
为了对各种汽车座椅的各项性能指标按国家标准进行检测,研制了多功能加载试验机。
Study on Tat Folate Mediated Magnetic Multi-functional Delivery System;
Tat、叶酸介导磁性复合功能载体系统的研究
The Transformation and Function of the Documents on A Dream of Red Mansions from Papery Carrier to Electronic Carrier;
红学文献从“纸质载体”到“电子载体”及其功能
Construction of rAAV2-GPIIb/GpIIIa Vector and Test of Its Expression and Function in Vitro;
rAAV2-GPIIb/GPIIIa载体构建和体外表达、功能实验
Construction of Recombinant Adenoviral Expressed Vector DMT1 and Its Functional Study;
DMT1腺病毒表达载体的构建和功能研究
Constructing of Plant Expression Vector of rd22 from Tamarix Ramosissima and Its Functional Verification;
柽柳rd22基因的载体构建及功能验证
Construction and Identification of Fruit-specific Expression Vectors;
果实特异性表达载体构建与功能鉴定
Silica-based Separation Carriers: Functionalization and Application
硅胶基质分离载体的功能化及其应用
Preparation and Application of Multifunctional Polymer Drug Carriers
多功能聚合物药物载体的制备及应用
Research on Functional Nanoparticles as Drug Carrier
功能化纳米粒子作为药物载体的研究
On ideological and political education,vector function of Quyi
论曲艺艺术的思想政治教育载体功能
Construction and Functional Identification of pSUPER Vector of p21 RNAi
p21 RNAi的pSUPER载体的构建及功能鉴定
Implementation of echo cancellation in application of vehicle multimedia navigation terminal
车载多媒体智能导航终端回声消除功能
On Modality,Characteristics And Function Of Chinese Net-cafe Business As A Cyber Culture Carrier
网吧作为网络文化载体的形态、特征和功能
Construction and Evaluation of Adenovirus Vector Retargeting to Tumor Vessel;
肿瘤血管靶向性腺病毒载体的构建及功能检测
Study on the Application of Functional Magnetic Carrier in Wastewater Treatment;
功能化磁性载体在水处理方面应用的研究
Construction and Evaluation of Adenovirus Vector Retargeting to Hematopoietic Cells;
血液细胞靶向性腺病毒载体的构建及功能检测
Construction and Functional Analysis of Eukaryotic Expression Vector of IT15 Gene Fragment in Huntington s Disease;
IT15基因片段真核表达载体的构建及其功能研究
Construction and Utilization of RNAi Vectors for the Functional Candidate Genes in Rice;
水稻功能候选基因RNA干涉载体的构建及其应用