The injury effect of oxygen stress and the protective effect of Yi-Xin-Kang capsule-containing serum on respiratory chain complex in rat myocardial mitochondria;
氧应激对体外大鼠心肌线粒体呼吸链复合物的损伤及益心康胶囊含药血清的保护作用
The mitochondrial respiratory Complex II or succinate:ubiquinone oxidoreductase (SQR) is an integral membrane protein complex in both the tricarboxylic acid cycle and aerobic respiration.
线粒体呼吸链复合物II即琥珀酸泛醌氧化还原酶(SQR)是一个跨膜蛋白复合物,复合物II由两个亲水蛋白(黄素蛋白和铁硫蛋白)和两个穿膜蛋白(CybL和CybS)构成,总的分子量大约在125kD左右,这里面包含了从琥珀酸到泛醌传递电子所需的电子传递体。
Objective:To observe the effect of the Heart Benefitting Recipe (HBR) on the oxidative stress “AD” rats spatial memory,brain mitochondrial respiratory function and respiratory enzyme activity.
结论 :调心方具有改善氧化损伤型类AD大鼠空间学习记忆障碍提高脑线粒体呼吸功能和呼吸链复合物酶活性作用 ,可能与其对抗自由基氧化损伤作用有