Objective To study the protective effects and mechanism of melatonin(MT) precondition on Parkinson disease(PD) brain slice of substantia nigra(SN,in vitro) induced by 6-hydroxydopamine(6-OHDA).
目的研究褪黑素(melatonin,MT)对6-羟多巴胺(6-hydroxydopamine,6-OHDA)所制造的离体帕金森病(Pakinson disease,PD)模型的影响。
METHODS:SD rat model of Parkinson s disease was established by lesion induction in substantia nigra compacta(SNc)by 6-hydroxydopamine.
方法:以6-羟多巴胺(6-OHDA)毁损黑质致密部(SNc)建立的PD模型大鼠为研究对象,采用玻璃微电极细胞外记录方法,记录和分析了PD状态下腹内侧前额叶皮层中神经元的电活动变化。
?Methods 6-hydroxydopamine(6-OHDA) was injected into the rats unilateral striatum.
方法成年大鼠单侧纹状体内注射6-羟多巴胺(6-hydroxydopamine,6-OHDA)。
Effects of 6-OHDA on the body weight and structure of small intestinal mucosa in mice;
6-羟多巴胺对小鼠体重及其小肠黏膜结构的影响
Objective To observe the morphologic changes of dopaminergic neurons in the substantia nigra of!Parkinson s disease (PD) rats that received a unilateral injection of 6-hydroxydopamine(6-OHDA).
目的观察6-羟多巴胺(6-OHDA)单侧注射制备的帕金森病(PD)大鼠多巴胺(DA)能神经元的超微结构改变。
Methods The model of sympathectomy mouse was established by injection of 6-OHDA intraperitoneally.
方法采用常规组织学和免疫组织化学技术,观察经腹腔注射交感神经损毁剂6-羟多巴胺后小鼠小肠上皮内淋巴细胞、杯状细胞、IgA+浆细胞、肥大细胞的数量分布变化。
Histopathological changes in the substantia nigra of Parkinson's disease rat model induced by 6-hydroxydopamine
应用6-羟基多巴胺建立帕金森病模型大鼠黑质神经组织病理学变化
Protective Action of Reduced Glutathione Against Toxicity of 6-hydroxy-dopamine on Bone Marrow Stromal Cells;
还原型谷胱甘肽拮抗6羟多巴胺对骨髓基质细胞的毒性作用
INFLUENCES OF INTRACEREBRAL INJECTION OF 6-OH-DA ON ACUPUNCTURE ANALGESIA AND MONOAMINERGIC NEURONS'HISTOFLUORESCENCE OF DORSAL RAPHE NUCLEUS
注射6-羟多巴胺于中缝背核后对针刺镇痛和单胺能神经元荧光组织化学反应的影响
Genetic Pathways Controlling the Development of Dompaminergic and Serotonergic Neurons
多巴胺和5-羟色胺神经元发育的基因调控途径
Protective Roles of Valproate Sodium on Apoptosis of Dopaminergic Neuron Induced by 6-OHDA;
丙戊酸钠对6-羟基多巴胺诱导的多巴胺能神经元凋亡的保护作用
Determination of dopamine-β-hydroxylase in rat serum and brain tissue by high performance liquid chromatography with electrochemical detector
高效液相色谱法测定多巴胺-β-羟化酶活性
EFFECT OF MIDAFLUR ON 5-HYDROXYTRYPTAMINE RE-LEASE AND DOPAMINE CONTENT IN RABBIT BRAIN
咪达氟对兔脑5-羟色胺释放和多巴胺含量的影响
Study on the Interaction between Dopaminergic and Serotonergic System in an Animal Model of Tourette Syndrome;
Tourette综合征动物模型脑内5-羟色胺和多巴胺系统相互作用的研究
Neuroprotective effects of deprenyl against 6-hydroxydopamine inducing neurotoxicity in PC12 cells
烷丙苯胺对6-羟基多巴胺致PC12细胞损伤的改善作用
Effect of DL-DOPA,L-5-HTP and Pentobarbital Sodium on Brain Encephalofluctuographs in rats
多巴、5-羟色胺酸和戊巴比妥钠对大白鼠脑涨落图的影响
Effects of medications on dopamine of rat corpus striatum treated with 6-OHDA
药物干预对6-羟基多巴胺处理大鼠的纹状体细胞外液多巴胺的影响
ASSOCIATION OF -1021C/T POLYMORPHISM IN DOPAMINE β HYDROXYLASE GENE WITH HEROIN DEPENDENCE
多巴胺β羟化酶基因-1021C/T多态性与海洛因依赖的相关性分析
CHANGE OF PREOPTIC OPIATE RECEPTORS AFTER INJECTION OF 6-OHDA INTO SUBLOCUS COERULEUS IN THE RABBIT
兔蓝斑下核内注入6-羟基多巴胺后视前区阿片受体的变化
Effect of Acupuncture Analgesia on Dopamine-β-Hyd roxylase Activity in Different Brain Areas and Adrenal Glands of Guinea Pig
针刺镇痛对豚鼠不同脑区及肾上腺多巴胺-β-羟化酶活性的影响
Proteomic Studies of Model of Parkinson Disease Induced by 6-Hydroxydopamine in PC12 Cells;
6-羟基多巴胺诱导的PC12细胞帕金森病模型的差异蛋白质组学研究
Protective Effects of Rosmarinic Acid Against 6-OHDA-induced Dopaminergic Neurodegeneration in MES23.5 Cells
迷迭香酸对6-羟基多巴胺处理的MES23.5细胞的保护作用研究
Study on the stability of establishment of Parkinson's disease (PD) model rats by injection 6-OHDA
6-羟基多巴胺所致帕金森病大鼠模型稳定性的研究
The Study on Drain Dopamine and Serotonin Concents of Uremia Encephalopathy Rat and on the Mechanism of Uremia Encephalopathy;
尿毒症脑病大鼠脑组织多巴胺、5-羟色胺含量变化及发病机制的探讨
Influence of Compatibility of Shenqi Pill "Reinforcing Yang from Yin" on the Contents of DA,5-HT in Hypothalamus of Deficient Kidney-Yang Rats
肾气丸“阴中求阳”配伍对肾阳虚大鼠下丘脑多巴胺及五羟色胺含量的影响
